Lab skills - Molecular Chemistry

Lab skills is a series of practicals scheduled for the same week, to give you an idea of what it's like to spend a week in a research lab.  The aim of this course is to brush up on the basics and learn more advanced techniques (set up of reactions under argon, the use of a vacuum ramp, management of syringe injections) so as to be ready for the internship. The program includes the multi-step synthesis of a ligand L and it’s use in a palladium-catalyzed cross coupling. To do so, the schedule is as follows: 

• Monday (all day): Synthesis of the first intermediate 
• Tuesday (morning): Synthesis of the second intermediate and launch the preparation of L (writing in the afternoon)
• Wednesday (all day): purification of L and launch the cross-coupling 
• Thursday (morning): NMR analysis of reaction mixture and pooling of results (writing in the afternoon)
• Friday: final analyses, writing and sending reports

Standard lab skills in organic synthesis