Biological Chemistry

This class will describe at the molecular level some principles governing the reactivity in enzymes and metallo-enzymes for different class of reactions (hydrolytic catalysis, redox catalysis) involved in different metabolic pathways. The focus will be made on the reaction mechanisms at the active sites.

• bioinorganic chemistry in a biological context:

- Presentation of the bio-inorganic domain

- Hydrolytic processes (hydrolysis of peptides)

- Redox reactions and dioxygen activation

• bioorganic chemistry in a biological context:

- Reaction mechanisms in bioorganic chemistry

- Metabolism of aminoacids

- Metabolism of carbohydrates

- Metabolism of nucleotides

knowledge and basic concepts in chemistry (organic and coordination chemistry, acid-base catalysis, redox reactions) and biochemistry (amino acids, proteins, enzymes, active site) from Bachelor’s degree